What is it about?

We have shown for the first time a simple and non expensive method to determine concentration of metformin in human urine. Samples of urine were collected by healthy volunteers in Albania. This method was applicable for a Bioequivalence Study using urine as a biological sample after administering Metformin Tablets. This method can be applied in every laboratory which a have conventional column and not a high budget.

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Why is it important?

Our findings show that with a conventional material and a cost-effective method we are able to determine concentration of Metformin in human urine and validate the method. Furthermore the validated method is applied for bioequivalence studies of humans to determine drug excretion in human urine after oral administration of metformin tablet.

Perspectives

It was a fantastic experience with Professor Leonard Deda who guided me through the process. The method was found to be rapid, precise, and accurate for quantification of metformin in human urine. This validated method was part of Bioequivalence Project which allowed us to determine Metformin in human urine.

PhD Eva Troja
Profarma Sh.a

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This page is a summary of: Quantification of Metformin in Human Urine by Using Ion-pair HPLC Method, August 2024, Sciencedomain International,
DOI: 10.9734/bpi/mmrnp/v2/1340.
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