AML generally shows aberrant CD expression or co- expression in relation to normal myeloid cells.

What is it about?

Objective of the Study was to evaluate the frequency and the pattern of aberrant CD expression in AML patients referred to a tertiary care hospital in Sri Lanka in comparison to other published data. There was no comparative data available in respect of Sri Lanka.

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Why is it important?

We conclude that aberrant expression of CD markers is seen in a significant population of AMLs. cyCD 3, CD7 and smCD 3 were the aberrant markers present in our study population . M0, M1, M2 & M4 AML are associated with aberrant expression. Of these cyCD3 was the commonest.