What is it about?
Curcumin, a natural compound in turmeric, has health benefits but dissolves poorly in water. By mixing it with special polymers (PEG) using heat, this study shows how its absorption improves, making it more effective for medicines.
Featured Image
Photo by Jellybee on Unsplash
Why is it important?
This work uniquely compares PEG 4000 and PEG 6000 in solid dispersions, revealing PEG 4000’s superior ability to enhance curcumin solubility. The fusion method transforms curcumin into an amorphous state, boosting dissolution by 4-fold. This timely approach addresses bioavailability challenges, offering a scalable solution for curcumin-based therapies.
Perspectives
Conducting this research highlighted the power of simple formulation techniques to solve complex bioavailability issues. Collaborating with peers to optimize polymer ratios was both challenging and rewarding. I’m hopeful these findings will inspire affordable, effective curcumin-based treatments, especially in resource-limited settings.
Yogesh Subhash Chaudhari
Dr. L. H. Hiranandani College of Pharmacy, Ulhasnagar
Read the Original
This page is a summary of: ENHANCEMENT OF SOLUBILITY AND DISSOLUTION RATE OF CURCUMIN BY SOLID DISPERSION TECHNIQUE, International Research Journal of Pharmacy, May 2013, Pan Health Care Research Society,
DOI: 10.7897/2230-8407.04548.
You can read the full text:
Contributors
The following have contributed to this page
