What is it about?
We found gamma-tubulin complex receptor can promote the oligomerization of gamma-tubulin complex. This process is regulated by phosphorylation of the receptor.
Featured Image
Why is it important?
1. Phosphorylation of Spc110 N-terminal domain (N-Spc110) regulates g-TuSC oligomerization. 2. Both SPM and CM1 are required for N-Spc110 to activate g-TuSC oligomerization. 3. The conserved N-Spc98 is required for Spc110-mediated oligomerization. 4. g-TuCRs can be categorized into CM1-only (Spc72/Mto1/Cnn/CDK5RAP2) and SPM-CM1 (Spc110/Pcp1/PCNT) type of receptors.
Read the Original
This page is a summary of: Cell-cycle dependent phosphorylation of yeast pericentrin regulates γ-TuSC-mediated microtubule nucleation, eLife, April 2014, eLife,
DOI: 10.7554/elife.02208.
You can read the full text:
Contributors
The following have contributed to this page
