What is it about?
Bioinformatic analysis of mass spectra of different bacterial species revealed recurring mass peaks in bacteria of the same species and genus. These mass peaks could thus be used in identifying specific species, and highlight deep biological basis in the use of mass spectrometry for identifying bacterial species.
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Why is it important?
The work reveals the existence of recurring mass peaks in mass spectra of different bacterial strains that help provide identification at the species and genus levels. Fundamentally, the work illustrates the biological principles that drive mass spectrometry-based microbial identification.
Perspectives
This work provides a direct link between evolutionary forces that shape the conservation of specific proteins and mass peaks, and their use for identification of the species and genus to which a strain belongs.
Wenfa Ng
National University of Singapore
Read the Original
This page is a summary of: Conserved mass peaks in MALDI-TOF mass spectra of bacterial species at the genus and species levels, May 2018, PeerJ,
DOI: 10.7287/peerj.preprints.3524v2.
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