What is it about?
Thiopyrano[2,3-d]thiazoles are cyclic isosteric mimetics of their synthetic precursors 5-arylidene-4-thiazolidinones without their typical negative features such Michael acceptors that are useless in the modern drug discovery process because of their low selectivity.
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Why is it important?
Our findings show that the synthesized compounds exhibited good anti-inflammatory activity compared with diclofenac sodium and ketorolac. Some of the compounds showed moderate antioxidant activity.
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This page is a summary of: Screening of antioxidant and anti-inflammatory activities among thiopyrano[2,3-d]thiazoles, Biopolymers and Cell, April 2015, Institute of Molecular Biology and Genetics (NAS Ukraine),
DOI: 10.7124/bc.0008d8.
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