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What is it about?
The study conducted a systematic literature search to identify relevant articles on the therapeutic properties of Nigella sativa, utilizing databases such as PubMed, Scopus, Web of Science, and Google Scholar. The research focused on articles published between July 1, 2000, and June 30, 2025, to ensure the inclusion of recent and evidence-based findings. Key terms used in the search included "Diabetes," "nanotechnology," "treatment," "management," "intervention," "outcome," and "efficacy." The study identified that Nigella sativa seeds contain significant amounts of bioactive compounds including thymoquinone (TQ), which is known for its therapeutic roles such as anti-inflammatory and analgesic effects. The research highlighted that N. sativa has been studied for its antioxidant, cytotoxic, and anti-cancer properties, demonstrating effects such as pro-apoptotic and anti-metastatic actions in cancer cell lines. The study concluded that N. sativa seeds and oil, due to their rich composition, could be valuable in developing therapeutic agents for diseases like cancer and diabetes.
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Why is it important?
This study is important as it underscores the therapeutic potential of Nigella sativa (black cumin seeds) in addressing major health concerns such as diabetes, cancer, and inflammatory diseases. By highlighting its diverse bioactive components, the research provides insights into how these natural compounds can be integrated into dietary and medicinal practices to promote health and prevent disease. The study's findings advocate for the inclusion of Nigella sativa in therapeutic regimes, potentially leading to the development of novel treatments and adjuvants that harness the plant's natural properties. This has significant implications for enhancing human health and managing chronic diseases through more natural and holistic approaches. Key Takeaways: 1. Diabetes Management: Nigella sativa has been shown to effectively lower blood sugar levels in diabetic patients, indicating its potential as a natural agent in diabetes management and treatment. 2. Anti-inflammatory and Analgesic Benefits: The study identifies thymoquinone (TQ) and other compounds in Nigella sativa as having substantial anti-inflammatory and analgesic effects, which could be beneficial in treating conditions like asthma, rheumatism, and bronchitis. 3. Cancer Prevention and Treatment: Nigella sativa exhibits antioxidant, pro-apoptotic, and anti-proliferative properties, suggesting its role in cancer prevention and as a supplementary treatment option in oncology due to its ability to inhibit cancer cell growth and metastasis.
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This page is a summary of: Therapeutic Properties of Nigella sativa (Black Cumin Seeds): A Review, Premier Journal of Plant Biology, October 2025, Premier Science,
DOI: 10.70389/pjpb.100022.
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