What is it about?
This study evaluated biochemical changes and hepatotoxic, genotoxic, and mutagenic effects of aqueous extract of the fruit of Morinda citrifolia (Family: Rubiaceae) in liver, bone marrow, and peripheral blood cells.
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Why is it important?
M. citrifolia is extensively used in traditional medicine due to its antiinflammatory, antimicrobial, antitumoral, and anti-hypertensive activities. However, there is no substantial data about hepatotoxic and toxicogenetic effects.
Perspectives
These findings suggest clastogenic and/or aneugenic effects and genetic instability activated by M. citrifolia, indicating precaution regarding the consumption of formulations or folk preparations based on this plant.
Dr. Muhammad Torequl Islam
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This page is a summary of: English, Journal of Medicinal Plants Research, January 2016, Academic Journals,
DOI: 10.5897/jmpr2015.6017.
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