What is it about?
This study confirms the effectiveness of 2% of the extract of the oak fruit hull in wound healing compared to 1% phenytoin cream, normal saline, and higher concentrations of plant extracts. Due to the side effects of chemical products, bacterial resistance to antibiotics, and secondary wound infections, effective herbal products in wound healing have received attention. The oak plant and its fruit hull have good antimicrobial, anti-inflammatory, and antioxidant effects and have good potential for use in wound healing products.
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Why is it important?
Our study scientifically validates the wound-healing potential of Persian oak (Quercus castaneifolia) fruit hull extract, a traditionally used but underexplored remedy. Results show it accelerates healing, and improves tensile strength and key growth factors (VEGF, PDGF), performing comparably to phenytoin. As demand for natural, cost-effective treatments grows, this work bridges traditional medicine with modern pharmacology, paving the way for clinical trials and innovative wound care solutions.
Perspectives
This research stands out for its ability to merge traditional medicine with modern scientific validation. Persian oak has long been valued in folk medicine, but this study provides concrete evidence of its effectiveness in wound healing. What I find particularly exciting is its potential to offer a natural, affordable alternative to conventional treatments which can have side effects. I look forward to seeing future studies that explore its application in human trials and possibly new herbal-based wound care products.
zeinab zaheri abdevand
Ahvaz Jondishapour University of Medical Sciences
Read the Original
This page is a summary of: Evaluating the Effectiveness of Aqueous Extract of Persian Oak (Quercus castaneifolia C.A.Mey.) Fruit Hull on Dermal Wound Healing in the Rat Model, Jundishapur Journal of Natural Pharmaceutical Products, August 2022, Kowsar Medical Institute,
DOI: 10.5812/jjnpp-127426.
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