What is it about?
This review evaluates the evolution and impact of clear aligner therapy (CAT) over the past 25 years. Since its introduction by Align Technology in 1999 as Invisalign, CAT has transformed orthodontic treatment with its clear, removable aligners.
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Why is it important?
Material and method: A comprehensive literature search was conducted across databases, including PubMed, Cochrane Library, ScienceDirect, Web of Science, Scopus, and Google Scholar, covering studies published from 2000 to 2025.
Perspectives
Origin and evolution Orthodontic interventions have proven effective in addressing both functional and aesthetic concerns in adult and pediatric populations [1]. Fixed appliances (FA) remain a cornerstone of comprehensive orthodontic treatment due to their proven efficacy in managing a wide range of malocclusions.
Acquire Publications
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This page is a summary of: The Evolution of Clear Aligner Therapy: A Review of Aesthetic and Clinical Outcomes, Journal of Dentistry and Oral Epidemiology, July 2025, Acquire Publications LLC,
DOI: 10.54289/jdoe2500106.
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