What is it about?
Vulvar Bowen’s disease, a rare form of vulvar intraepithelial neoplasia (VIN III), represents a precancerous lesion mostly linked to high-risk human papillomavirus (HPV) infection. Diagnosis is often delayed due to non-specific clinical presentation mimicking benign dermatoses.
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Why is it important?
We report the case of a 63-year-old woman with a chronic pruritic vulvar lesion initially treated unsuccessfully with topical corticosteroids. Biopsy confirmed HPV-associated Bowen-type VIN III.
Perspectives
Bowen’s disease is a form of intraepithelial squamous cell carcinoma, first described by John T. Bowen in 1912 [1]. When it affects the vulva, it falls within the spectrum of vulvar intraepithelial neoplasia (VIN), representing a non-invasive precancerous entity. It is frequently associated with persistent high-risk human papillomavirus (HPV) infection, particularly types 16 and 18 [2].
Acquire Publications
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This page is a summary of: Refractory Vulvar Bowen’s Disease: A Case Report and Literature Review, Journal of Case Reports and Medical History, October 2025, Acquire Publications LLC,
DOI: 10.54289/jcrmh2500152.
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