What is it about?
Uterine smooth muscle tumor of uncertain malignant potential (STUMP) is a rare tumor. They are classified as benign leiomyoma and malignant leiomyosarcoma regarding presence of tumor cell necrosis, cytological atypia and mitotic activity. STUMP is regarded in World Health Organization (WHO) classification as smooth muscle tumors between benign and malignant criteria.
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Why is it important?
STUMP is seen mostly in age of mid-forties, who has been operated with preoperative leiomyoma diagnosis. Risk factors and prognosis are not fully understood, but in long-term follow-up, there is a potential of recurrence or metastasis.
Perspectives
According to the World Health Organization (2003), uterine smooth muscle tumor of uncertain malignant potential (STUMP) is a borderline tumor between benign leiomyoma and malignant leiomyosarcoma ;It is difficult for an even skilled pathologist to diagnose STUMP by identifying detailed markers such as cytologic atypia, mitotic activity, or tumor cell necrosis that distinguish leiomyoma from leiomyosarcoma
Acquire Publications
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This page is a summary of: About Two Cases of Uterine Smooth Muscle Tumor of Uncertain Malignant Potential, Journal of Case Reports and Medical History, August 2025, Acquire Publications LLC,
DOI: 10.54289/jcrmh2500149.
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