What is it about?
Introduction: Large intracardiac thrombi generally require surgical removal, yet some cases have shown a favorable response to anticoagulation therapy alone. This report highlights a case involving substantial left ventricular thrombi, which posed a significant risk of systemic embolization but unexpectedly resolved completely with standard heparin anticoagulation.
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Why is it important?
Case Report: A 50-year-old woman receiving vinorelbine and trastuzumab for metastatic breast cancer was admitted with symptoms of right-sided heart failure. Transthoracic echocardiography identified two highly mobile echogenic masses attached to the left ventricular wall, consistent with thrombi. The patient was started on low-molecularweight heparin alongside standard heart failure treatment. Remarkably, follow-up echocardiography within 48 hours demonstrated complete resolution of the thrombi.
Perspectives
Intracardiac thrombi, particularly large and mobile ones, are often treated with surgical thrombectomy. However, certain cases involving soft, hypo-echoic thrombi have responded well to anticoagulation therapy, albeit requiring more than a week for resolution. This report presents a unique case where large left ventricular thrombi, posing a high risk of systemic embolization, dissolved rapidly following conventional heparin anticoagulation.
Acquire Publications
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This page is a summary of: Unraveling the Enigmaquick Disappearance of a Cardiac Clot in a Patient Undergoing Treatment for Breast Cancer a Case Report, Journal of Case Reports and Medical History, January 2025, Acquire Publications LLC,
DOI: 10.54289/jcrmh2500102.
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