What is it about?
Intracranial calcification can occur physiologically in some cases, typically without symptoms and is discovered incidentally through neuroimaging. However, pathological calcification in the basal ganglia is often caused by underlying conditions such as metabolic disorders, infections, and genetic diseases.
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Why is it important?
Here we present a 50-year-old male presented with multiple episodes of generalised tonic-clonic seizures. A brain CT scan revealed extensive symmetrical basal ganglia and periventricular calcification. Further testing showed low calcium levels, high phosphorus levels, and low parathyroid hormone levels, leading to a diagnosis of primary hypoparathyroidism and thereby Fahr Syndrome.
Perspectives
Primary hypoparathyroidism is a rare endocrine disorder characterized by low calcium levels (hypocalcaemia) due to insufficient or absent parathyroid hormone (PTH) production by the parathyroid glands.
Acquire Publications
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This page is a summary of: Seizures and Basal Ganglia Calcification Secondary to Hypoparathyroidism: Fahr Syndrome an Intriguing Presentation, Journal of Case Reports and Medical History, January 2025, Acquire Publications LLC,
DOI: 10.54289/jcrmh2500101.
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