What is it about?
Paget’s disease of the breast is a particular form of the disease that occurs in 1 to 4% of breast cancers. It is characterised by an accumulation of abnormal cells known as "PAGET cells" in the epidermis of the nipple, associated with underlying glandular cancer in 82 to 100% of cases [1].
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Photo by National Cancer Institute on Unsplash
Why is it important?
Clinically, it presents as eczematous eruptions on the nipple and areola, often unilateral. Imaging based on ultrasound mammography and magnetic resonance imaging of the breast is therefore useful in searching for underlying cancer. Its management and prognosis are conditioned by the accompanying breast cancer.
Perspectives
The patient was 60 years old, naïve, with no previous pathological history, and presented with an eczematous lesion of the right nipple. The lesion had begun a year earlier as a scaly, pruritic patch involving the nipple and areola of the right breast. Clinical examination revealed an inflammatory plaque on the right nipple, ulcerated in places and topped with a crust (Figure 1).
Acquire Publications
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This page is a summary of: Paget’s Disease of the Nipple: A Case Report and Review of the Literature, Journal of Case Reports and Medical History, December 2024, Acquire Publications LLC,
DOI: 10.54289/jcrmh2400157.
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