What is it about?

Malignant degeneration of benign cystic teratoma of the ovary is a rare complication occurring mostly during post-menopausal period. The malignant transformation of the benign teratoma has no specific clinical nor radiological, nor biological signs.

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Why is it important?

The treatment is surgical and preferentially similar to that of epithelial tumors of the ovary. We report an observation of a squamous cell carcinoma developed on a mature cystic teratoma of the ovary, in a patient aged 59 years, revealed by the final histopathological exam of an adnexectomy with a mature teratoma of the ovary.

Perspectives

Teratomas of the ovary are the most common germ cell tumours, with mature teratomas of the ovary occurring in 10-20% of cases [1]. Malignant transformation of one or more components of mature teratomas is rare, occurring in around 1-2% of cases [2]. Carcinogenesis may lead to squamous cell carcinoma in 80% of cases, adenocarcinoma or, rarely, sarcoma [3].

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This page is a summary of: Malignant degeneration of benign cystic teratoma of the ovary : A Report Case, Journal of Case Reports and Medical History, June 2024, Acquire Publications LLC,
DOI: 10.54289/jcrmh2400142.
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