What is it about?

Autoimmune polyglandular syndromes (APS) are a rare heterogeneous disorders characterized by combining two or more organ-specific endocrinopathies. During pregnancy, only a few cases of these syndromes have been described. We report a case of autoimmune polyglandular syndrome type 2 presenting during pregnancy and complicated in the immediate postpartum by a severe polyserositis.

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Why is it important?

Autoimmune polyglandular syndromes (APS) are rare inherited disorders characterized by multiple endocrine dysfunction. Based on clinical presentation, they are classified into three types. Types 1 and 2 are well-characterized entities, whereas type 3 is poorly characterized [1].

Perspectives

The presence of lymphocytic infiltration of the affected glands, organ-specific autoantibodies in serum, and an association with HLA linkage genes support the autoimmune nature of these disorders [1].

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This page is a summary of: A Rare Case of an Autoimmune Polyglandular Syndrome Type 2 During Pregnancy, Journal of Case Reports and Medical History, July 2024, Acquire Publications LLC,
DOI: 10.54289/jcrmh2400135.
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