What is it about?
Primary Biliary Cholangitis (PBC), formerly known as primary biliary cirrhosis, is an autoimmune-related cholestatic hepatopathy, representing a common cause of intrahepatic cholestasis due to progressive bile duct destruction.
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Why is it important?
Often, PBC is linked with other autoimmune disorders such as Sjogren’s syndrome, thyroid dysfunction, scleroderma, and systemic lupus erythematosus. However, the association of PBC with rheumatoid arthritis (RA) is rare, estimated at 1.8 to 5.6%. We present a clinical case of PBC discovered in a patient with deforming rheumatoid arthritis.
Perspectives
The coexistence of Primary Biliary Cholangitis (PBC) and Rheumatoid Arthritis (RA) raises intriguing questions about the intricate interplay of autoimmune processes within the body. PBC, once considered a distinct liver disorder, is increasingly recognized for its association with various autoimmune conditions. While PBC is commonly linked with diseases such as Sjogren’s syndrome and scleroderma, the convergence with RA remains a rare phenomenon.
Acquire Publications
Read the Original
This page is a summary of: Primary Biliary Cholangitis and Rheumatoid Arthritis: An Emerging Association, Journal of Case Reports and Medical History, February 2024, Acquire Publications LLC,
DOI: 10.54289/jcrmh2400113.
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