What is it about?
Sarcoidosis is a systemic disease of unknown etiology. It is characterized by the presence of noncaseating granulomatous lesions in the affected organs. Primary biliary cirrhosis (PBC) is a chronic autoimmune cholestatic hepatopathy characterized by destruction of the bile ducts and the presence of M2-type anti-mitochondrial antibodies [1].
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Why is it important?
The association of sarcoidosis and primary biliary cirrhosis reported here is rare. It poses a problem of histological differential diagnosis and raises the hypothesis of an etiopathogenic link between the two conditions [2].
Perspectives
This is a 49-year-old patient admitted for etiological assessment of bilateral granulomatous uveitis, who has been presenting with inflammatory arthralgias involving both knees, both ankles, both elbows and both wrists for 5 years, the two elbows and the two wrists associated with an ocular involvement made of a bilateral granulomatous uveitis and a dry syndrome the symptomatology was enriched two months later by the appearance of a dyspnea stage II with in the thoracic CT a diffuse interstitial pneumopathy and the appearance of a pruritus ²generalized the whole evolving in a context of conservation of the general state.
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This page is a summary of: Association of Sarcoidosis and Primary Biliary Cirrhosis: A New Observation, Journal of Case Reports and Medical History, December 2023, Acquire Publications LLC,
DOI: 10.54289/jcrmh2300143.
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