What is it about?

Autoimmune hemolytic anemia (AIHA) is a pathological process involving the destruction of red blood cells by the humoral immune system. Although there is a well-established relationship between the presence of AIHA and lymphoproliferative malignancies, AIHA rarely presents in association with solid malignancies.

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Why is it important?

Few cases of solid cancer associated with AIHA have been reported. AIHA rarely presents as a paraneoplastic syndrome indicative of solid cancer. We report a case of breast cancer revealed by AIHA.

Perspectives

The paraneoplastic manifestation of hemolytic anemia in patients with solid tumors is often a sign of poor prognosis. In rare cases, it is a feature of an occult primary malignant neoplasm. Hemolysis usually occurs late in the course of the disease and manifests abruptly as severe anemia. We report a case of hemolytic anemia in breast carcinoma.

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This page is a summary of: Breast Cancer and Autoimmune Hemolytic Anemia: A Rare Paraneoplastic Syndrome, Journal of Case Reports and Medical History, December 2023, Acquire Publications LLC,
DOI: 10.54289/jcrmh2300142.
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