What is it about?
We followed blood from 20 healthy donors during 20 days of storage in local blood banks. Samples were examined every five days using blood counts, light and scanning electron microscopy, and osmotic fragility testing. Red cells progressively lost their normal shape, their number and haemoglobin fell, and more than two-thirds appeared abnormal by day 20.
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Why is it important?
These findings show that storage-related damage develops progressively and makes red cells more fragile. Understanding when these changes appear can support blood-bank quality monitoring and research on safer transfusion practices, especially for patients who need repeated transfusions or have enlarged liver or spleen.
Perspectives
From my perspective, this work matters because These findings show that storage-related damage develops progressively and makes red cells more fragile. I hope the findings support further research and informed, evidence-based decisions.
Yasar Yousafzai
Khyber Medical University
Read the Original
This page is a summary of: Time dependent changes in red blood cells during storage in the local blood banks of Khyber Pakhtunkhwa, Journal of the Pakistan Medical Association, October 2020, Pakistan Medical Association,
DOI: 10.47391/jpma.676.
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