What is it about?
To evaluate the effect of BoTA injected with ultrasonographic guidance into the muscle tissue that the perforator pedicle is arisen from one month ago on the perfusion of flap scintigraphically and the survival rate of SPPP flap in a rat model.
Featured Image
Photo by DAVIDCOHEN on Unsplash
Why is it important?
In a rat model, if with the ultrasonographic guidance, BoTA is injected to the muscle which perforator of the prospective SPPP flap originated and flap surgery is performed one month later after this injection, the perfusion of SPPP flap increases scintigraphically and this improves flap survival and reduces its necrosis.
Perspectives
We did with the current experimental study, in a rat model, BotoluniumToxin-A was injected into the muscle which gives rise to perforators. This resulted in increased flap perfusion and improved the survival of flap prepared as fasciocutaneous single-perforator-pedicled propeller flap and rotated at 180° in the clockwise direction. According to these findings, intramuscular BoTA injection, before the use of fasciocutaneous single-perforator-pedicled propeller flap, has the potential to be used as an experimental drug in studies about flap survival and scintigraphy can be used as a modality to assess the perfusion of flaps before suturing its place.
Nese Kurt Ozkaya
Cumhuriyet Universitesi
Read the Original
This page is a summary of: Effect of Botulinum Toxin-A Injected to Muscle Tissue on Perfusion and Survival of Fasciocutaneous Single Perforator-pedicled Propeller Flap in Rats, Balkan Medical Journal, February 2020, Journal of Clinical Research of Pediatric Endocrinology,
DOI: 10.4274/balkanmedj.galenos.2019.2019.9.44.
You can read the full text:
Contributors
The following have contributed to this page
