What is it about?
After receiving stem cell transplantation, the host response to foreign antigens is mediated through cytokines. Some cytokines are pro and some are protective from graft vs. host disease. The balance between both parties determines the risk to develop GVHD
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Why is it important?
GVHD is the most serious complication of stem cell transplantation largely jeopardizing its therapeutic potential.
Perspectives
The potential of predicting the occurrence or severity of GVHD would have great clinical impact and would appreciably improve the outcome of stem cell transplantation
Professor Azza M Kamel
NCI, Cairo University
Read the Original
This page is a summary of: Interferon Gamma/IL10 Ratio Production in Response to Host Antigens may Predict Acute Graft Versus Host Disease after Allogeneic Stem Cell Transplantation from a Sibling, Journal of Leukemia, January 2013, OMICS Publishing Group,
DOI: 10.4172/2329-6917.1000111.
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