What is it about?
With the increasing incidence of hypertension globally, more attention must be drawn on the autoimmune disorders that go with the use of anti hypertensives. This subject is an emerging cause of morbidity and mortality. This study showed relative decrease in mean hematocrit level of female hypertensive patients on therapy compared to their counterpart contol group (p>0.05) with no evident positive Direct Anti globulin Test.
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Why is it important?
Apart from the autoimmune sensitization which may result from the use of some anti hypertensives, this group of drugs may cause other direct hematological disorders without necessarily triggering autoimmune sensitization. For instance, drug-induced haemolytic anaemia (DIHA) could result with or without drug-induced immune hemolytic anemia (DIIHA). Further studies with a larger sample size and longer duration of follow-up will held to improve the validity of our result.
Perspectives
Writing this article has enabled me to collaborate with my co-authors and colleagues in cardiology and nephrology units. It gave more insight into the values of multi-disciplinary showmanship in the management of patient. I hope that the National Institute of Heart Lung and Blood Diseases (NIHLBD) and other similar research institutes will find this article thought-provoking in terms of research funding of future research projects on similar subject.
Dr Ogbonna Collins Nwabuko
Federal Medical Center, Umuahia.
Read the Original
This page is a summary of: A Prospective Assessment of Autoimmune Sensitization of Hypertensive Patients on Antihypertensive Therapy: A Hospital Based Study, Journal of Blood & Lymph, January 2017, OMICS Publishing Group,
DOI: 10.4172/2165-7831.1000183.
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