What is it about?
hypo/hyperthyroidism alters the neuronal cytoskeleton and neuronal growth either by affecting the developmental programs for expression of specific isoforms
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Why is it important?
thyroid disorders during the development can disrupt the cytoskeleton system, mitochondrial functions and gene expression.
Perspectives
Further work is therefore required to determine whether normalization of circulatory THs levels can prevent the disturbance of fetal brain cytoskeletal protein expression.
Full Professor Ahmed R. G.
Division of Anatomy and Embryology, Zoology department, Faculty of Science, Beni-Suef University, Egypt.
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This page is a summary of: Perinatal Hypothyroidism and Cytoskeleton Dysfunction, Endocrinology & Metabolic Syndrome, January 2017, OMICS Publishing Group,
DOI: 10.4172/2161-1017.1000271.
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