The Electrophysiological Memory Function of Hippocampus Different from O′Keefe and Mosers

What is it about?

The electrophysiology of hippocampus demonstrated by O’Keefe and Mosers is yet unattainable to explain the same memory function of mammillary bodies. The limbic-reticular coupling theory I proposed previously suggested the descending limbic system regulate the ascending reticular systems to consolidate and recall declarative memories. On electrophysiology, the hippocampal CA3 neurons can regulate the raphe nuclei and ventral tegmental area in their activities, while the cholinergic-mediated gamma wave is also coupled to theta activities. In this way, through these limbic-reticular electrophysiological couplings, the hippocampus can synchronously recall several components of a memory dispersed in various cortical areas. Therefore, here is outlined the alternative part of hippocampal electrophysiology on memory recall different from O’Keefe and Mosers.

Featured Image

Photo by Keren Fedida on Unsplash

Photo by Keren Fedida on Unsplash

Why is it important?

This limbic-reticular coupling theory is supported for memory recall while O’Keefe and Mosers did not consider such electrophysiology as theta-gamma coupling etc.

Perspectives