Enhancing anticancer activity through the combination of bioreducing agents and triterpenes

Barbara Bednarczyk-Cwynar, Piotr Ruszkowski, Tomasz Jarosz, Katarzyna Krukiewicz
  • Future Medicinal Chemistry, February 2018, Future Science
  • DOI: 10.4155/fmc-2017-0154

Anticancer activity of triterpenes

What is it about?

A way to increase the anticancer activity of triterpenes by modifying their structure with a bioreducing agent. The paper describes the synthesis of nitro-modified triterpene, as well as its characterization from the point of view of electrochemistry, spectroelectrochemistry and anti-cancer efficiency.

Perspectives

Katarzyna Krukiewicz
Silesian University of Technology

We believe this approach to the functionalization is promising in terms of enhancing anticancer activity. We also indicate electrochemical techniques as advantageous preclinical screening methods for the identification of cytotoxic agents.

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http://dx.doi.org/10.4155/fmc-2017-0154

The following have contributed to this page: Katarzyna Krukiewicz