What is it about?
B19V infection is associated with a wide spectrum of clinical manifestations, some of which were well established and some are still controversial, however, it is also underestimated from a clinical perspective.
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Why is it important?
The pattern of genetic evolution, its peculiar properties and functional profile, the characteristics of its narrow tropism and restricted replication, its complex relationship with the host and its ample pathogenetic potential are all topics that are far from a comprehensive understanding.
Perspectives
The lack of efficient adaptation to in vitro cellular cultures and the absence of animal models have limited classical virological studies and made studies on B19V dependent on molecular biology.
LAWAL DAHIRU ROGO
BAYERO UNIVERSITY KANO
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This page is a summary of: Human parvovirus B19: A review, Acta Virologica, January 2014, AEPress, s.r.o.,
DOI: 10.4149/av_2014_03_199.
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