Helicobacter pylori Infection in Dyspeptic adults

What is it about?

Accurate detection of Helicobacter pylori infection is crucial for properly treating patients with dyspepsia. Several invasive and non‑invasive diagnostic methods are being utilized. Aims: This study aimed to determine the prevalence of H. pylori in adult patients with dyspeptic conditions and how it related to endoscopic findings, histological features, and the relationship to urea breath test (UBT) results.

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Why is it important?

The study included 68 females (37 H. pylori positive and 31 H. pylori negative) and 32 males (13 with H. pylori and 19 without H. pylori) with a female‑to‑male ratio of 2.1:1. The most common endoscopic finding was nodularity in 28 patients (46%) who were H. pylori positive and 5 (10%) who were H. pylori negative, followed by gastritis, erosive gastritis, erythema, hiatus hernia, and gastric ulcer. The most common histological feature was chronic gastritis in 52 cases (64%) in the positive bacterial cases and 20 (36%) in the negative group, with a statistically significant relationship. There was a significant difference between histopathological findings with both endoscopic examination and UBT results for H. pylori positive and negative patients.

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