What is it about?
HIV infection is a global healthcare problem. Sub-Saharan Africa accounts for about 70% of all persons living with HIV. HIV is known to affect the kidneys. The degree to which the kidneys are affected and the factors which influence this impact by HIV are not completely known especially in the early stage.
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Why is it important?
This study demonstrated a high prevalence of CKD in treatment-naive HIV subjects in Owerri, Nigeria. The study used a combination of GFR (glomerular filtration rate) and proteinuria (presence of protein in 24-hour urine) to define CKD. Low waist circumference, high serum creatinine, high spot urine protein/creatinine ratio, high 24-hour urine protein-creatinine ratio, high 24-hour urine protein-osmolality ratio were predictors of CKD in HIV subjects.
Perspectives
CKD prevalence is high (22.9%) among newly-diagnozed HIV subjects in southeast Nigeria.. Low waist circumference, proteinuria, and 24-hour urine protein-creatinine ratio as well as 24-hour urine protein osmolality ratio are predictors of CKD,. These hypothetical ratios have not been previously evaluated in CKD in both the general population and HIV subgroup.
Dr Ernest Ndukaife Anyabolu
Chukwueneka Odumegwu Ojukwu University, Awka, Nigeria
Read the Original
This page is a summary of: Prevalence and predictors of chronic kidney disease in newly diagnosed human immunodeficiency virus patients in Owerri, Nigeria, Indian Journal of Nephrology, January 2016, Medknow,
DOI: 10.4103/0971-4065.156115.
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