What is it about?

Probiotic as one of the biomedical factors affecting cognition plays an important role in supporting the gut-brain axis. While several studies have reviewed the effect of probiotics in adults, reviews in children and adolescents are lacking. This review aimed to systematically evaluate the effect of probiotic interventions on cognitive function in children and adolescents.

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Why is it important?

This is the first review to evaluate the effect of probiotic supplementation on cognitive function in children and adolescents. Our findings show that the favourable effect of probiotic supplementation on cognitive function in children and adolescents was observed in one study with Lactobacillus rhamnosus GG supplementation by a risk reduction of developing attention deficit hyperactivity disorder (ADHD) or Asperger syndrome (AS) (ie. autism).

Perspectives

It is very interesting that a number of studies have intensively discussed the impact of gut-brain axis on brain function, yet our study found that there are merely a few randomized controlled trials investigating the effect of probiotics on child and adolescent cognitive development. This study also highlights that more RCTs are warranted to identify the strains which are capable to support brain development in childhood and adolescence.

Davrina Rianda
Universitas Indonesia

Read the Original

This page is a summary of: Effect of probiotic supplementation on cognitive function in children and adolescents: a systematic review of randomised trials, Beneficial Microbes, November 2019, Wageningen Academic Publishers, DOI: 10.3920/bm2019.0068.
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