What is it about?

The aim of our study is to present serum mTOR and SESN 1 levels by comparing patients with or without bone fractures

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Why is it important?

The evaluation of the relationship between these serum proteins and the pathway occurring in response to bone fracture may also guide further studies describing the bone healing process. Therefore, in this study, we aimed to compare serum mTOR and SESN-1 levels in patients with or without bone fracture.

Perspectives

According to our results, the serum mTOR levels increased the first day after fracture compared to a control group. However, we obtained no significant difference between groups in terms of SESN-1 levels. This study may guide further clinical studies investigating the potential role of mTOR signaling in the bone healing process.

Özhan Pazarcı
Cumhuriyet Universitesi

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This page is a summary of: Does the mammalian target of rapamycin and sestrin 1 protein signaling have a role in bone fracture healing?, TURKISH JOURNAL OF MEDICAL SCIENCES, January 2019, The Scientific and Technological Research Council of Turkey,
DOI: 10.3906/sag-1809-117.
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