What is it about?

In recent years, the serrated neoplasia pathway where serrated polyps arise as a colorectal cancer has gained considerable attention as a new carcinogenic pathway.

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Why is it important?

Colorectal serrated polyps are histopathologically classified into hyperplastic polyps (HPs), sessile serrated lesions, and traditional serrated adenomas; in the serrated neoplasia pathway, the latter two are considered to be premalignant. In western countries, all colorectal polyps, including serrated polyps, apart from diminutive rectosigmoid HPs are removed. However, in Asian countries, the treatment strategy for colorectal serrated polyps has remained unestablished.

Perspectives

Therefore, in this review, we described the clinicopathological features of colorectal serrated polyps and proposed removing HPs and sessile serrated lesions ≥ 6 mm in size, and traditional serrated adenomas of any size.

Dr Wataru Sano
Sano Hospital

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This page is a summary of: Serrated polyps of the colon and rectum: Remove or not?, World Journal of Gastroenterology, May 2020, Baishideng Publishing Group Co., Limited (formerly WJG Press),
DOI: 10.3748/wjg.v26.i19.2276.
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