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Methylene blue (MB) staining has been studied in various gastrointestinal organs over the past years. We present two cases of esophagogastroduodenoscopy and endoscopic ultrasound -guided MB injection to facilitate therapeutic upper endoscopic interventions. The first case reports MB injection to facilitate pancreatic duct orifice localization and cannulation after unsuccessful endoscopic retrograde cholangiopancreatography, and the second case reports MB injection to identify gastric staple line fistula. The two cases highlight the feasibility of MB as an adjunct in upper endoscopic interventions.

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This page is a summary of: Clue by the Blue: Using Methylene Blue as an Adjunct to Facilitate Access and Therapeutic Upper Endoscopic Interventions, Innovations in Surgery and Interventional Medicine, January 2025, Innovative Healthcare Institute,
DOI: 10.36401/isim-24-04.
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