The Occurrence of Senescence in the Arteriovenous Fistula in the Rat

What is it about?

The dialysis arteriovenous fistula is the preferred vascular access for dialysis. However, there is a high failure rate for dialysis vascular accesses. We demonstrate that accelerated aging processes contribute to failure of a pre-clinical model of fistula. This is clinically relevant because drugs that slow aging are now undergoing clinical trials.

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