Clinical Characteristics and Kidney Outcomes in Chinese Patients with Autosomal Dominant Polycystic Kidney Disease

What is it about?

The Mayo Clinic imaging classification allows a more accurate risk stratification for polycystic kidney disease, but it is limited by the lack of data on non-Caucasian populations and on atypical imaging patterns. We aim to assess the clinical characteristics and the morphology of the cystic kidneys in a cohort of Chinese patients with polycystic kidney disease. In this cohort, an atypical imaging pattern was observed in 17% of the cases, associated with later presentation and a milder disease course. Future genotyping studies will help to define the genetic architecture and the basis for the phenotypic spectrum in Chinese ADPKD patients.

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