What is it about?
The N-terminal arm of the ubiquitous enzyme proline dehydrogenase (ProDH) differs in length, dependent on the organism. We have studied the functional impact of this arm in a thermophilic ProDH by shortening the arm with deletion mutagenesis.
Featured Image
Why is it important?
Shortening the length of this arm gives insight in the importance of this arm for the catalytic and structural properties of ProDH and provides important information about the aggregation behaviour of ProDH.
Perspectives
This study forms a good basis for getting more insight into the evolutionary relationship of ProDH and its interaction with cellular partners.
Professor Willem J.H. van Berkel
Wageningen University
Read the Original
This page is a summary of: Functional Impact of the N-terminal Arm of Proline Dehydrogenase from Thermus thermophilus, Molecules, January 2018, MDPI AG,
DOI: 10.3390/molecules23010184.
You can read the full text:
Contributors
The following have contributed to this page
