The N-terminal arm of proline dehydrogenase
What is it about?
The N-terminal arm of the ubiquitous enzyme proline dehydrogenase (ProDH) differs in length, dependent on the organism. We have studied the functional impact of this arm in a thermophilic ProDH by shortening the arm with deletion mutagenesis.
Why is it important?
Shortening the length of this arm gives insight in the importance of this arm for the catalytic and structural properties of ProDH and provides important information about the aggregation behaviour of ProDH.
The following have contributed to this page: Professor Willem J.H. van Berkel