What is it about?
Cell-based therapies have the potential to revolutionize current treatments for diseases with high prevalence and related economic and social burden. Unfortunately, clinical trials have made only modest improvements in restoring normal function to degenerating tissues. Authors review the major factors that hamper successful cell engraftment and the strategies that have been studied to enhance the beneficial effects of cell therapy. Moreover, we provide a perspective on whether mesenchymal stromal cell-derived extracellular vesicle delivery, as a cell-free regenerative approach, may circumvent current cell therapy limitations.
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This page is a summary of: Challenges and Strategies for Improving the Regenerative Effects of Mesenchymal Stromal Cell-Based Therapies, International Journal of Molecular Sciences, October 2017, MDPI AG,
DOI: 10.3390/ijms18102087.
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Challenges and Strategies for Improving the Regenerative Effects of Mesenchymal Stromal Cell-Based Therapies
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