What is it about?
The precise tuning of lipolysis is imperative to prevent lipotoxicity, obesity, diabetes and other related metabolic disorders. Here, we present our finding that miR-124a attenuates RNA and protein expression of the major TG hydrolase, ATGL/PNPLA2 and its co-activator CGI-58/ABHD5.
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Why is it important?
miR-124a may be involved in the regulation of several cellular and organismal metabolic parameters, including lipid storage and plasma FA concentration.
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This page is a summary of: Micro RNA-124a Regulates Lipolysis via Adipose Triglyceride Lipase and Comparative Gene Identification 58, International Journal of Molecular Sciences, April 2015, MDPI AG,
DOI: 10.3390/ijms16048555.
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