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Authors determined that copper depletion using a specific chelating agent reduces proliferation, survival and migration of human colon cancer cells bearing the BRAFV600E mutation acting through inhibition of the mitogen-activated (MAP) kinase pathway.
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This page is a summary of: Effects of Copper Chelation on BRAFV600E Positive Colon Carcinoma Cells, Cancers, May 2019, MDPI AG,
DOI: 10.3390/cancers11050659.
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The Chang Lab Webpage
The Chang Lab Webpage at the University of California, Berkeley, Dept of Chemistry
The Su Laboratory Publications
The Su Laboratory Publications University of California
The Heffern Lab Publications
The Heffern Lab Publications
Intestinal Cell News
Intestinal Cell News Volume 5.18 | May 24 2019
Current biomedical use of copper chelation therapy
Int J Mol Sci. 2020; 21(3): 1069. doi: 10.3390/ijms21031069.
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Roles of Copper in Cancer
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