What is it about?
Periodontitis has been associated with systemic diseases such as cerebrovascular events. Emerging research highlights the potential role of the microbiome in intracranial aneurysm formation and rupture. Here, we explored the associations among periodontal pathogens and the outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH).
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Why is it important?
Elevated hsCRP and IL-6 levels, periodontal pocket depth ≥ 5 mm, and red-complex periodontal pathogens are associated with an increased risk of delayed cerebral ischemia (DCI) after aSAH, suggesting a role for periodontal disease–related systemic inflammation in DCI risk stratification.
Perspectives
Oral health status, particularly the presence of deep periodontal pockets and some specific pathogenic bacteria, may represent a modifiable risk factor in the complex management of aSAH patients.
Tihamer Molnar
University of Pecs, Medical School, Hungary
Read the Original
This page is a summary of: Periodontal Bacteria and Outcomes Following Aneurysmal Subarachnoid Hemorrhage: A Prospective Observational Analysis, Biomedicines, December 2025, MDPI AG,
DOI: 10.3390/biomedicines14010048.
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