What is it about?

Regulation of channels that mediate direct cell to cell communication. Role of calmodulin

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Why is it important?

Knowledge of the mechanism that regulates direct communication between neighboring cells is important as altered communication is causing various diseases

Perspectives

This publication reviews various mechanisms that allow cells to gate their direct intercellular exchange of ions and other small molecules

Camillo Peracchia

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This page is a summary of: Gap Junction Channel Regulation: A Tale of Two Gates—Voltage Sensitivity of the Chemical Gate and Chemical Sensitivity of the Fast Voltage Gate, International Journal of Molecular Sciences, January 2024, MDPI AG,
DOI: 10.3390/ijms25020982.
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