What is it about?

This study proposes the use of multi-class classifiers instead of the traditional binary classifiers when the targeted disease may have an overlap with another know disease. We study this in a dementia dataset containing alzheimer disease, frontotemporal disease and healthy controls.

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Why is it important?

This is the first study to shed light on the importance of, and the need for, multi-class prediction models in neuroimaging, and medical image analysis in general. We present how that can be conducted, and exhibit new technology to analyze classification performance of multi-class classifiers.

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This page is a summary of: Three-Class Differential Diagnosis among Alzheimer Disease, Frontotemporal Dementia, and Controls, Frontiers in Neurology, May 2014, Frontiers,
DOI: 10.3389/fneur.2014.00071.
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