What is it about?
Hemodynamics is the study of blood flow dynamics within the circulatory system. It explores the physical laws governing blood movement through blood vessels. Hemodynamics focuses on understanding how blood flows, the forces involved, and the factors affecting circulation. Blood flow ensures the transport of nutrients, hormones, waste products, oxygen, and carbon dioxide throughout the body. It maintains cell-level metabolism, regulates pH, osmotic pressure, and temperature, and protects against harm. Blood is a complex liquid, not a simple Newtonian fluid. Its viscosity and behavior differ due to the presence of formed elements (platelets, white blood cells, and red blood cells) and their interaction with plasma molecules. Conductance cardiac-based catheters like the one developed in 1984, allow advanced hemodynamic evaluations in clinical settings. Researchers use pressure-volume (PV) relationships to assess cardiovascular function after interventions (genetic, pharmacologic, or surgical) in Cath-laboratories worldwide.
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Why is it important?
In summary, hemodynamics plays a crucial role in understanding blood flow and cardiovascular function, benefiting both research and clinical practice. While conductance catheters provide deep insights into cardiac function, their daily use requires a solid theoretical background and careful interpretation.
Perspectives
Objectives of Novel studies and modeling: Modeling cardiac contractility in pre-clinical catheterization labs aims to assess systolic and diastolic indices under controlled hemodynamic conditions. Early Indicators of Heart Failure: Hemodynamic monitoring using pressure-volume modeling helps identify early signs of heart failure (HF). End Systolic Elastance (Ees): Ees is a systolic index of contractility. It’s essential for understanding cardiac function. Older and novel approaches are compared in this context. Standardized Maneuver: Inferior vena cava occlusion (IVCO) is a common technique to assess contractile responsiveness. It reduces preload transiently. Novel Approaches: Exploring other indices, such as single-beat systolic PPESPVR and IVCO using end-systolic (ES) points, offers unique research opportunities.
Dr. Filip Konecny
University of South Florida
Read the Original
This page is a summary of: Editorial: Advanced invasive hemodynamics: pressure-volume maneuvers to obtain load-independent indices, Frontiers in Cardiovascular Medicine, August 2024, Frontiers,
DOI: 10.3389/fcvm.2024.1468811.
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