What is it about?

Haemodialysis patients are more prone to have infection with hepatitis B virus although Hepatitis B vaccine is effective in producing protection against this infection. in this study we observed that haemodialysis patients showed a better antibody response to hepatitis B vaccine after the administration of an extra 4th dose than the primary vaccine series comprising of three doses.

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Why is it important?

HBV infections are common and a major threat to patients treated with long-term haemodialysis (HD), and have a tendency to become chronic carriers of HBV due to defective immune system. Patients with chronic kidney disease (CKD), especially if diabetic, have a reduced response to vaccination because of the general immune suppression associated with uremia and our study reports the response rates of hepatitis B vaccine among maintenance haemodialysis patients.

Perspectives

I hope, this article will help clinicians to take decision on prescribing the dose schedule of hepatitis B vaccine for chronic kidney disease patients.

Kamrun Nahar
Sheikh Fazilatunnessa Mujib Memorial KPJ Specialized Hospital and Nursing College

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This page is a summary of: Antibody responses after hepatitis B vaccination among maintenance haemodialysis patients, Bangladesh Medical Research Council Bulletin, December 2011, Bangladesh Journals Online (BanglaJOL),
DOI: 10.3329/bmrcb.v37i3.9119.
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