What is it about?

β-lactolin is a whey-derived Gly-Thr-Trp-Tyr peptide rich in fermented dairy products, which improves human cognitive peformance of memory retrieval and attention in older adults. The current study evaluated the effects of β-lactolin on Alzheimer's disease. β-lactolin reduced inflammation in the brain and Aβ-deposition and improved memory imapairment in Alzheimer's disease model 5×FAD mice.

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Why is it important?

Our findings showed that β-lactolin reduces the inflammation in the brain and prevents Alzheimer's disease in mice. The results supprt the previous demonstrated clinical trials and eipidemiological investigations.


The daily cunsumption of β-lactolin might be beneficial for the prevention of cognitive decline or dementia in elderly.

Yasuhisa Ano
Kirin Holdings Kabushiki Kaisha

Read the Original

This page is a summary of: β-Lactolin, a Whey-Derived Lacto-Tetrapeptide, Prevents Alzheimer’s Disease Pathologies and Cognitive Decline, Journal of Alzheimer s Disease, February 2020, IOS Press, DOI: 10.3233/jad-190997.
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