What is it about?

We present a new open source software (OS) package called Spherical Brain Mapping (SBM), which can be used to extract relevant information from three-dimensional medical images. This information summarizes the texture of the brain from the inside out using magnetic resonance imaging, and can be displayed as if it were a map. The use of SBM helped us predict the onset of Alzheimer's Disease with high acuracy.

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Why is it important?

Alzheimer's Disease affects 46 million people around the globe. It is the main cause of dementia, but its diagnosis still remains a challenge. An early diagnosis is crucial for alleviating its symptoms and provide a better quality of life for patients and their closer environment. SBM could be used in clinical practice to automatically create alerts of possible Alzheimer, providing relevant information for the diagnosis procedure.

Perspectives

This work was the final step of more than 3 years working intermitently on the python and matlab versions of the package. We finally achieved great accuracy in diagnosing Mild-Cognitive Impairment (a very complicated task), producing very informative 2D brain texture maps that might help in further understanding the disease.

Francisco Jesus Martinez-Murcia
Universidad de Granada

Read the Original

This page is a summary of: Assessing Mild Cognitive Impairment Progression using a Spherical Brain Mapping of Magnetic Resonance Imaging, Journal of Alzheimer’s Disease, September 2018, IOS Press,
DOI: 10.3233/jad-170403.
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