What is it about?

Case report of a patient who expired due to propofol infusion syndrome

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Why is it important?

Discusses propofol infusion syndrome and why prolonged propofol infusions should not be used as sedation especially in pediatric patients


This case report discusses the unfortunate case of a teenager who suffered a severe closed head injury and was being cared for at a referring hospital. She subsequently developed discolored urine which was consistent with propofol infusion syndrome. The propofol infusion was discontinued and she was transferred to our institution. The patient exhibited severe metabolic acidosis, rhabdomyolysis, and ultimately cardiovascular collapse less than one day after arriving at our institution.

Michael Cannon MD
Wake Forest University

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This page is a summary of: Metabolic acidosis, rhabdomyolysis, and cardiovascular collapse after prolonged propofol infusion, Journal of Neurosurgery, December 2001, Journal of Neurosurgery Publishing Group (JNSPG), DOI: 10.3171/jns.2001.95.6.1053.
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