What is it about?

Ozone has been found to have potent antiinflammatory effects, to activate the immune system, and to have a substantial impact on the antioxidant system. In this study the authors aimed to evaluate the neuroprotective effects of ozone and their possible roles in recovery from spine injury, assessed based on biochemical, histological, and neurological parameters using an experimental spine injury model in rats.

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Why is it important?

Ozone was found to have a greater antiinflammatory effect, hasten clinical recovery, and increase histological recovery compared with methylprednisolone therapy alone. This study showed that this combination therapy of methylprednisolone with the addition of ozone might have a more beneficial effect in the treatment of spinal injury than methylprednisolone therapy alone.


This experimental study is a study that will be representative of new treatment strategies in people with spinal cord injury, and it also has a rewiew feature, since serious effort has been made and at the same time as the sum of the main tests in the literature.

Izmir Katip Celebi Universitesi

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This page is a summary of: Evaluation of the neuroprotective effects of ozone in an experimental spine injury model, Journal of Neurosurgery Spine, September 2020, Journal of Neurosurgery Publishing Group (JNSPG), DOI: 10.3171/2020.2.spine191439.
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