What is it about?

Intracranial GCTs are relatively common brain tumors in Asian children. The late adverse events due to treatment will be evaluated from the follow-up of about 10 years.

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Why is it important?

Radiation therapy for intracranial GCTS causes late adverse events such as abnormal hormone production and visual / hearing impairment, and in some cases leads to psychiatric disorders. Even if the radiation dose is low, microbleeds occurs frequently. Some of these could only be evaluated after 10 years or more of follow-up.


Pediatric intracranial GCTs are a rare disease and their data are important. We would be honored if the valuable data obtained through careful examination for more than 10 years would be useful for future medical treatment.

Akinori Takada
Mie university hospital

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This page is a summary of: Long-term follow-up of intensive chemotherapy followed by reduced-dose and reduced-field irradiation for intracranial germ cell tumor, Journal of Neurosurgery Pediatrics, March 2019, Journal of Neurosurgery Publishing Group (JNSPG), DOI: 10.3171/2018.9.peds18181.
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